AOD9604 is a modified hgh fragment supplied by Apex Laboratory as a high-purity research peptide intended strictly for in-vitro laboratory research and development applications.
Compound Overview
AOD9604 is a modified 16-amino acid peptide fragment corresponding to the C-terminal region of human growth hormone (amino acids 176-191). It was specifically designed to isolate the lipolytic activity of hGH while excluding somatotropic effects. Research has examined its interaction with beta-3 adrenergic receptor signaling and fat metabolism pathways.
Research Background & Published Literature
Originally developed by Metabolic Pharmaceuticals and studied at Monash University, AOD9604 has been investigated in adipose tissue metabolism research. Published studies have explored its effects on lipogenesis inhibition and lipolysis stimulation in adipocyte models. It received GRAS (Generally Recognized as Safe) status from the FDA as a food ingredient in 2011.
Researchers interested in the published literature surrounding this compound can explore the following peer-reviewed resources for additional context on its mechanism of action, signaling pathways, and experimental applications in controlled laboratory settings:
- Heffernan et al. (2001) — hGH fragment lipolytic action research
- Ng et al. (2003) — AOD9604 adipose tissue signaling
Technical Specifications
- Product Name: AOD9604
- Classification: Modified hGH Fragment
- Structural Description: 16-amino acid fragment of human growth hormone (hGH 176-191) with an N-terminal tyrosine
- CAS Number: 221231-10-3
- Molecular Weight: 1815.08 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
Storage, Handling & Stability Guidelines
Store lyophilized AOD9604 at -20°C. Its relatively small size (16 amino acids) provides good lyophilized stability. Reconstituted material should be stored at 2–8°C and used within 14 days.
- Minimize time at ambient temperature during handling to preserve compound integrity.
- Avoid moisture exposure by resealing vials promptly after each withdrawal.
- Use appropriate personal protective equipment and follow your institution’s chemical safety protocols at all times.
- Label all aliquots with the compound name, concentration, date of reconstitution, and operator initials for complete traceability.
Quality Assurance & Analytical Verification
Apex Laboratory applies a dual-verification quality protocol to every batch before it enters inventory. Each lot undergoes High-Performance Liquid Chromatography (HPLC) to confirm chromatographic purity and Mass Spectrometry (MS) to verify molecular identity and molecular weight. This two-step analytical process ensures that the material you receive meets our ≥99% purity standard with confirmed molecular integrity. Certificates of Analysis documenting these results are available upon request for your internal quality records.
Frequently Asked Questions
How is AOD9604 related to human growth hormone?
AOD9604 corresponds to amino acids 176-191 of human growth hormone with an additional N-terminal tyrosine modification. It was engineered to retain the lipolytic properties of hGH without somatotropic activity.
What is the CAS number of AOD9604?
AOD9604 has CAS number 221231-10-3 and a molecular weight of 1815.08 g/mol.
Is this product approved for human use?
No. All compounds sold by Apex Laboratory are classified as chemical research reagents intended strictly for in-vitro laboratory research. They are not approved for human consumption, veterinary use, or any therapeutic application. Purchasers who imply intended bodily use will have their orders cancelled and accounts permanently suspended.
What documentation is available for this compound?
Certificates of Analysis (COA) with HPLC chromatograms and Mass Spectrometry data are available for current batches. Contact our support team at support@apexlaboratory.org before ordering if your laboratory requires specific documentation to satisfy internal quality review or regulatory compliance workflows.
Is bulk ordering available?
Yes. For bulk quantities, custom packaging requirements, or recurring supply agreements, contact our team with the compound name, desired quantity, preferred dosage format, and your target delivery timeline. Volume pricing is available for qualifying orders.
Related Research Compounds
Researchers studying modified hgh fragment pathways may also be interested in related compounds available from Apex Laboratory, including HGH Fragment 176-191, Ipamorelin, CJC-1295 No DAC. Explore our complete research catalog to browse all available peptides, reagents, and laboratory supplies, or visit our About page to learn more about our quality verification process.
Shipping, Packaging & Delivery
All orders placed before 2:00 PM Eastern Standard Time ship the same business day via tracked domestic carriers. Products are packaged in insulated, temperature-appropriate containers designed to preserve compound stability during transit. Upon delivery, transfer all materials to appropriate storage conditions immediately. For time-sensitive research protocols or special delivery requirements, contact our support team in advance to coordinate optimal shipping timing for your laboratory workflow.
Research Use Disclaimer
For in-vitro research use only. Not for human consumption. All products sold by Apex Laboratory are intended exclusively for qualified researchers, accredited laboratories, and educational institutions. Purchasers assume full responsibility for ensuring safe handling, proper storage, and compliance with all applicable federal, state, and local laws, regulations, and institutional policies governing the purchase and use of chemical research reagents.
