Melanotan I 10mg is a mc1r-selective melanocortin agonist supplied by Apex Laboratory as a high-purity research peptide intended strictly for in-vitro laboratory research and development applications.
Compound Overview
Melanotan I (afamelanotide) is a linear tridecapeptide analog of α-melanocyte-stimulating hormone. It demonstrates selectivity for the MC1R receptor compared to other melanocortin receptor subtypes, making it a valuable tool for studying melanogenesis signaling specifically through MC1R-mediated pathways.
Research Background & Published Literature
Afamelanotide has been investigated in clinical settings for erythropoietic protoporphyria (EPP) and is marketed under the brand name Scenesse in certain regions. Laboratory research focuses on MC1R-selective signaling, eumelanin synthesis, and photoprotection pathways.
Researchers interested in the published literature surrounding this compound can explore the following peer-reviewed resources for additional context on its mechanism of action, signaling pathways, and experimental applications in controlled laboratory settings:
- Hadley and Dorr (1996) — Melanocortin peptide therapeutic potential
- Langendonk et al. (2015) — Afamelanotide EPP clinical study
Technical Specifications
- Product Name: Melanotan I 10mg
- Classification: MC1R-Selective Melanocortin Agonist
- Structural Description: Linear 13-amino acid peptide analog of α-MSH (also known as Afamelanotide)
- CAS Number: 75921-69-6
- Molecular Weight: 1646.85 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
Storage, Handling & Stability Guidelines
Store lyophilized Melanotan I at -20°C. Linear peptide structure may be slightly less stable than cyclic analogs. Reconstituted material should be used within 14 days when stored at 2–8°C.
- Minimize time at ambient temperature during handling to preserve compound integrity.
- Avoid moisture exposure by resealing vials promptly after each withdrawal.
- Use appropriate personal protective equipment and follow your institution’s chemical safety protocols at all times.
- Label all aliquots with the compound name, concentration, date of reconstitution, and operator initials for complete traceability.
Quality Assurance & Analytical Verification
Apex Laboratory applies a dual-verification quality protocol to every batch before it enters inventory. Each lot undergoes High-Performance Liquid Chromatography (HPLC) to confirm chromatographic purity and Mass Spectrometry (MS) to verify molecular identity and molecular weight. This two-step analytical process ensures that the material you receive meets our ≥99% purity standard with confirmed molecular integrity. Certificates of Analysis documenting these results are available upon request for your internal quality records.
Frequently Asked Questions
What is the difference between Melanotan I and Melanotan II?
Melanotan I (afamelanotide) is a linear 13-amino acid peptide with selectivity for MC1R. Melanotan II is a cyclic 7-amino acid peptide that acts non-selectively across MC1R–MC5R. Melanotan I is used when MC1R-specific signaling is the research focus.
Is Melanotan I the same as afamelanotide?
Yes. Melanotan I and afamelanotide refer to the same compound — a linear 13-amino acid analog of α-MSH with CAS 75921-69-6 and molecular weight 1646.85 g/mol.
Is this product approved for human use?
No. All compounds sold by Apex Laboratory are classified as chemical research reagents intended strictly for in-vitro laboratory research. They are not approved for human consumption, veterinary use, or any therapeutic application. Purchasers who imply intended bodily use will have their orders cancelled and accounts permanently suspended.
What documentation is available for this compound?
Certificates of Analysis (COA) with HPLC chromatograms and Mass Spectrometry data are available for current batches. Contact our support team at support@apexlaboratory.org before ordering if your laboratory requires specific documentation to satisfy internal quality review or regulatory compliance workflows.
Is bulk ordering available?
Yes. For bulk quantities, custom packaging requirements, or recurring supply agreements, contact our team with the compound name, desired quantity, preferred dosage format, and your target delivery timeline. Volume pricing is available for qualifying orders.
Related Research Compounds
Researchers studying mc1r-selective melanocortin agonist pathways may also be interested in related compounds available from Apex Laboratory, including Melanotan II 10mg, PT-141 10mg, GHK-Cu. Explore our complete research catalog to browse all available peptides, reagents, and laboratory supplies, or visit our About page to learn more about our quality verification process.
Shipping, Packaging & Delivery
All orders placed before 2:00 PM Eastern Standard Time ship the same business day via tracked domestic carriers. Products are packaged in insulated, temperature-appropriate containers designed to preserve compound stability during transit. Upon delivery, transfer all materials to appropriate storage conditions immediately. For time-sensitive research protocols or special delivery requirements, contact our support team in advance to coordinate optimal shipping timing for your laboratory workflow.
Research Use Disclaimer
For in-vitro research use only. Not for human consumption. All products sold by Apex Laboratory are intended exclusively for qualified researchers, accredited laboratories, and educational institutions. Purchasers assume full responsibility for ensuring safe handling, proper storage, and compliance with all applicable federal, state, and local laws, regulations, and institutional policies governing the purchase and use of chemical research reagents.
